Code: EU14652
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Description Tykerb 250 mg Novartis
Specification Tykerb 250 mg Novartis
Features
Active substance
Lapatinib
Also known as
GW572016
Blood pressure
Can cause decreases in left ventricular ejection fraction, monitoring advised
Chemical name
N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]quinazolin-4-amine
Dosage (medical)
Typically 1250 mg once daily, taken in combination with capecitabine
Dosage (sports)
Not applicable
Effects
Reduces the growth of cancer cells in patients with breast cancer overexpressing HER2
Formula
C29H26ClFN4O4S
Half-life
Approximately 24 hours
Hepatotoxicity
Possible, liver function tests should be monitored
Lab Test
Monitoring of liver enzymes and bilirubin levels
Main action
Inhibits human epidermal growth factor receptor (HER) 2 and EGFR tyrosine kinases
Side effects
Diarrhea, rash, nausea, fatigue, vomiting, mouth sores
Storage conditions
Store at room temperature, protect from moisture and heat
Strength
250mg
Substance class
Tyrosine kinase inhibitor
Trade name
Tykerb, Tyverb
Use in sports
Not used in sports
Water Retention
Minimal to none
Manufacturer
Novartis Ltd.
Packing
30 tabs/bottle
Reviews